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Index > Protein center > Zp3(Gene name) > Mouse
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  • Zp3 (Gene name),
  • Zona pellucida sperm-binding protein 3 (Protein name ),  ZP3_MOUSE from NCBI database.
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  • Gene name:
    Zp3(Zp-3;Zpc);
    Protein name:
    Zona pellucida sperm-binding protein 3;
    Alternative:
    Zona pellucida glycoprotein 3(Zp-3);Sperm receptor;Zona pellucida protein C;
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Polymers of ZP2 and ZP3 organized into long filaments cross-linked by ZP1 homodimers.
    Function:
    The mammalian zona pellucida, which mediates species-specific sperm binding, induction of the acrosome reaction and prevents post-fertilization polyspermy, is composed of three to four glycoproteins, ZP1, ZP2, ZP3, and ZP4. ZP3 is essential for sperm binding and zona matrix formation.
    Subcellular Location:
    Cell membrane Single-pass type I membrane protein
    Protein Attributes:
    Sequence length:
    424
    Sequence:
    50:
    MASSYFLFLC | LLLCGGPELC | NSQTLWLLPG | GTPTPVGSSS | PVKVECLEAE | 
    100:
    LVVTVSRDLF | GTGKLVQPGD | LTLGSEGCQP | RVSVDTDVVR | FNAQLHECSS | 
    150:
    RVQMTKDALV | YSTFLLHDPR | PVSGLSILRT | NRVEVPIECR | YPRQGNVSSH | 
    200:
    PIQPTWVPFR | ATVSSEEKLA | FSLRLMEENW | NTEKSAPTFH | LGEVAHLQAE | 
    250:
    VQTGSHLPLQ | LFVDHCVATP | SPLPDPNSSP | YHFIVDFHGC | LVDGLSESFS | 
    300:
    AFQVPRPRPE | TLQFTVDVFH | FANSSRNTLY | ITCHLKVAPA | NQIPDKLNKA | 
    350:
    CSFNKTSQSW | LPVEGDADIC | DCCSHGNCSN | SSSSQFQIHG | PRQWSKLVSR | 
    400:
    NRRHVTDEAD | VTVGPLIFLG | KANDQTVEGW | TASAQTSVAL | GLGLATVAFL | 
    424:
    TLAAIVLAVT | RKCHSSSYLV | SLPQ
    3D Structure:
    N/A
    Predicted Eptitope:
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    EIAab Sequence  Vaild Sequence:
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    Related Databases
    UniGene:
    Pfam:
    SMR:
    KEGG:
    String:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse Zona pellucida sperm-binding protein 3
    Cat.:
    E11951h
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    96T
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    ELISA Kit for Mouse Zona pellucida sperm-binding protein 3
    MSDS:
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    ELISA Kit for Mouse Zona pellucida sperm-binding protein 3
    MSDS:
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    ELISA Kit for Mouse Zona pellucida sperm-binding protein 3
    MSDS:
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    ELISA Kit for Mouse Zona pellucida sperm-binding protein 3
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    ELISA Kit for Mouse Zona pellucida sperm-binding protein 3
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    Packing:
    96T
    ELISA Kit for Mouse Zona pellucida sperm-binding protein 3
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    ELISA Kit for Mouse Zona pellucida sperm-binding protein 3
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    CLIA Kit for Mouse Zona pellucida sperm-binding protein 3
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    Packing:
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    CLIA Kit for Mouse Zona pellucida sperm-binding protein 3
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    CLIA Kit for Mouse Zona pellucida sperm-binding protein 3
    MSDS:
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    CLIA Kit for Mouse Zona pellucida sperm-binding protein 3
    MSDS:
    Please sign in first.
    CLIA Kit for Mouse Zona pellucida sperm-binding protein 3
    MSDS:
    Please sign in first.
    CLIA Kit for Mouse Zona pellucida sperm-binding protein 3
    MSDS:
    Please sign in first.
    CLIA Kit for Mouse Zona pellucida sperm-binding protein 3
    Cat.:
    U11951h
    Price:
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    MSDS:
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    Packing:
    96T
    Range:
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    CLIA Kit for Mouse Zona pellucida sperm-binding protein 3
    Cat.:
    U11951r
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    Packing:
    96T
    Polyclonal Antibody for Mouse Zona pellucida sperm-binding protein 3
    Polyclonal Antibody for Mouse Zona pellucida sperm-binding protein 3
    Polyclonal Antibody for Mouse Zona pellucida sperm-binding protein 3
    Polyclonal Antibody for Mouse Zona pellucida sperm-binding protein 3
    Polyclonal Antibody for Mouse Zona pellucida sperm-binding protein 3
    Polyclonal Antibody for Mouse Zona pellucida sperm-binding protein 3
    Polyclonal Antibody for Mouse Zona pellucida sperm-binding protein 3
    Polyclonal Antibody for Mouse Zona pellucida sperm-binding protein 3
    Cat.:
    P11951Rb-h
    Price:
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    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Mouse Zona pellucida sperm-binding protein 3
    Monoclonal Antibody for Mouse Zona pellucida sperm-binding protein 3
    Monoclonal Antibody for Mouse Zona pellucida sperm-binding protein 3
    Monoclonal Antibody for Mouse Zona pellucida sperm-binding protein 3
    Monoclonal Antibody for Mouse Zona pellucida sperm-binding protein 3
    Monoclonal Antibody for Mouse Zona pellucida sperm-binding protein 3
    Monoclonal Antibody for Mouse Zona pellucida sperm-binding protein 3
    Monoclonal Antibody for Mouse Zona pellucida sperm-binding protein 3
    Protein for Mouse Zona pellucida sperm-binding protein 3
    Protein for Mouse Zona pellucida sperm-binding protein 3
    Protein for Mouse Zona pellucida sperm-binding protein 3
    Protein for Mouse Zona pellucida sperm-binding protein 3
    Protein for Mouse Zona pellucida sperm-binding protein 3
    Protein for Mouse Zona pellucida sperm-binding protein 3
    Protein for Mouse Zona pellucida sperm-binding protein 3
    Protein for Mouse Zona pellucida sperm-binding protein 3

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    References
    1. 1.
      "Molecular analysis of cDNA coding for ZP3, a sperm binding protein of the mouse zona pellucida."
      Ringuette M.J. , Chamberlin M.E. , Baur A.W. , Sobieski D.A. , Dean J.
      Dev. Biol.127:287-295(1988) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    2. 2.
      Dean J.
      Submitted (1996-11) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SEQUENCE REVISION TO 387
    3. 3.
      "Nucleotide sequence of the gene encoding zona pellucida glycoprotein ZP3 -- the mouse sperm receptor."
      Kinloch R.A. , Wassarman P.M.
      Nucleic Acids Res.17:2861-2863(1989) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
      strain: CD-1.
      tissue: Liver.
    4. 4.
      "Primary structure of the mouse sperm receptor polypeptide determined by genomic cloning."
      Kinloch R.A. , Roller R.J. , Fimiani C.M. , Wassarman D.A. , Wassarman P.M.
      Proc. Natl. Acad. Sci. U.S.A.85:6409-6413(1988) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
    5. 5.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
    6. 6.
      "Identification of a region of mouse zona pellucida glycoprotein mZP3 that possesses sperm receptor activity."
      Rosiere T.K. , Wassarman P.M.
      Dev. Biol.154:309-317(1992) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 49-63; 197-204; 219-233 AND 261-275
      strain: CD-1.
    7. 7.
      "Structural characterization of native mouse zona pellucida proteins using mass spectrometry."
      Boja E.S. , Hoodbhoy T. , Fales H.M. , Dean J.
      J. Biol. Chem.278:34189-34202(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF C-TERMINUS;PYROGLUTAMATE FORMATION AT GLN-23;DISULFIDE BOND FORMATION AT 78-CYS--CYS-98; 216-CYS--CYS-283 AND 240-CYS--CYS-301;GLYCOSYLATION AT ASN-146; ASN-273; ASN-304; ASN-327 AND ASN-330;IDENTIFICATION BY MASS SPECTROMETRY
    8. 8.
      "Crystal structure of the ZP-N domain of ZP3 reveals the core fold of animal egg coats."
      Monne M. , Han L. , Schwend T. , Burendahl S. , Jovine L.
      Nature456:653-657(2008) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.3 ANGSTROMS) OF 42-143;IDENTIFICATION BY MASS SPECTROMETRY;MUTAGENESIS OF TYR-111;SUBCELLULAR LOCATION;DISULFIDE BONDS
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